ASD shows in early childhood as mild to severe deficits in social interaction, learning, and language. Cases often include stereotypic and impulsive behaviors, food allergies, and seizures.(1-7)
Most cases are not genetic. Although about 100 gene mutations have been found in children with ASD, they explain only about 3% of cases. Most cases therefore, are triggered by events after birth.(8)
Some researchers have tried to explain the astronomic increase in ASD as earlier diagnosis and better diagnostic tests, which find cases that would previously have been missed, and include milder cases that previously would not have been counted. Together, however, these improvements explain only 25% of the increased cases.(9)
Other researchers have suggested that the increase in ASD stems from an unintended effect of improvement in maternal nutrition. Since 1996, folate has been added to some US foods, and women are also advised to take additional folic acid during pregnancy. This additional folate in the diet promotes proper development of the brain and spinal cord during pregnancy and weaning. It has prevented many thousands of cases of spina bifida and other developmental disorders in the fetal brain and spinal cord.(10,11)
After weaning, however, the infant diet in the US often becomes short on folate. For many it becomes a junkfood diet dominated by cereals, fast foods, baked goods, and sodas, with up to one quarter of its total calories from nutrition-less sugar, mainly from high-fructose-corn-syrup a man-made sugar (not to be confused with fructose which is a natural fruit sugar). Almost all cereals, baked goods and sodas are now sweetened with high-fructose-corn-syrup.(12-13)
Consequently, although the brain is the most robust organ in the body, it gradually loses ground in development, often beginning to show ASD by age 3. Overall, however, the folate deficiency theory of the increase in ASD accounts for no more than 10% of the increased cases.(14,16)
Together the three above causes of ASD, genetic problems,(3%) better diagnosis,(25%) and folate deficiency in the infant,(10%) explain less than 40% of the increase in ASD over the last 20 years. So over 60% of all cases today must be caused by increased environmental stress.
The biggest change in environmental stress over the last 20 years is the huge increase in man-made chemicals that now pervade our lives. Many of these industrial and agricultural chemicals were once thought to be harmless, and used freely. But they have now proven to be highly toxic. Primarily because of political weakness, they continue to be produced and used in vast quantities. They occur widely in our air, water, food, household products, cosmetics, furniture, and building materials.(17)
In 2002, the worst were called by scientists “The Dirty Dozen and listed for banning worldwide. Few have yet been banned, and many more new toxins have been introduced. There are now more than 30 classes of chemicals on the list. They include dioxins, polychlorinated biphenyls (PCBs) of which there are over 200 different types, chlorinated and organo-phosphate pesticides (the original chemical basis of Nazi nerve gases), which now include, endrin, dieldrin, aldrin, chlordane, toxaphene, heptachlor, mirex, and hexachlorobenzene), brominated flame retardants (BFR), plasticizers such as bisphenol A, nonylphenol, and phthalates, and surfactants, such as perfluorooctanoic acid (PFOA).(17)
These chemicals damage hormone-dependent processes in the body and disrupt functioning of human endocrine glands. They have now been officially classified as endocrine-disrupting chemicals (EDCs). EDCs noted above also damage neural transmission and the formation of neural networks in the infant brain.(17-21 )
EDCs are resistant to physical, chemical and biological degradation. Unless specifically cleaned up, they remain active in the environment for decades. Because they are mostly lipophilic (mix easily with fats), they accumulate in many human and animal cells and tissues. EDCs accumulate and concentrate rapidly as they move up the food chain, often reaching high levels in large food animals, such as beef, which leads to high concentrations in us.
Research shows clearly that even very low doses of EDCs can cause incomplete growth of specific regions of the infant brain and thereby impair brain functions.(17-21) They are almost certainly the cause of many cases of Autism Spectrum Disorder today.
EDC chemicals not only damage brains of infants, but also the brains of their parents.(22, 23) The biggest problem is: by the time the victims realize that they have been poisoned, often their brains are so damaged they have insufficient wits left to pursue their case.
Even national authorities seem powerless against the thrust of profitable toxins. With great fanfare, the Environmental Protection Agency (EPA) was formed in1976 to protect the American public after terrible chemical poisonings in the US, such as the infamous Love Canal. Now, 38 years later we know that they have failed miserably to halt the spread of manufactured toxins into the environment.
In the political choice between health and commerce, commerce almost always wins. The 2013 report of the American Lung Association for example, shows that the air in major American cities is dirtier now than ever before in history.(24) The general response of the EPA to this evidence is emotional bluster, denial, and legal obfuscation. As Fox News reported on 18 March 2014, if you try to get any credible information from this agency – Good Luck !(25)
Our major weapon is the ballot box. But all parties in each election use the most sophisticated behavior modification techniques to covertly manipulate voter attention to jobs, the economy, and national security, all of which are of minor value if you do not have your health.
As we have seen with the turmoil over Obama’s Affordable Care Act over the last five years, national health will always be a fight against vested interests. For those who agree that our personal health and that of our families should be our first concern, the next election is the time to stand up and be counted. Vote only for those who make cleaning up the environment front and center on their agenda.
Meanwhile, avoid all the chemical toxins you can. It’s time to clean up our act.
For all adults we recommend using a regular body cleansing system to help your system remove as many of these chemicals as possible. For what we recommend go to this page.
1. Theoharides TC,et al The genetics of autism. Pediatrics.2004;113(5):472–486.
2. Fombonne E: Epidemiology of pervasive developmental disorders.
Pediatric Research 2009, 65:591-598.
3. Tuchman R, Rapin I: Epilepsy in autism. Lancet Neurol 2002, 1:352-358.
4. Hertz-Picciotto I, Delwiche L. The rise in autism and the role of age at diagnosis. Epidemiology 2009 ; 20 (1): 84 -90.
5. Autism and Other Developmental Disabilities Monitoring Network. Prevalence of autism spectrum disorders: Autism and Developmental Disabilities Monitoring Network, United States,. MMWR. 2009;58(SS-10):2–21.
6. Abrahams BS, Geschwind DH. Advances in autism genetics: on the threshold of a new neurobiology. Nat Rev Genet. 2008;10:341–355. doi: 10.1038/nrg2346. McPartland J, Volkmar FR. Autism and related disorders.Handb Clin Neurol. 2012;10:407–418.
7. Williams SC. Genetics: searching for answers. Nature.2012;10:S4–S6. doi: 10.1038/491S4a.
8. A case series of a luteolin formulation (NeuroProtek®) in children with autism spectrum disorders. Int J Immunopathol Pharmacol. 2012 Apr-Jun;25(2):317-23.
9. Barskey AE, Glasser JW, LeBaron CW. Mumps resurgences in the United States: A historical perspective on unexpected elements. JAMA. 2013 Feb 13;309(6):570-7. doi: 10.1001/jama.2012.155925. Vaccine. 2009 Oct 19;27(44):6186-95.
10. Chiappini E, et al. Pertussis re-emergence in the post-vaccination era. BMC Infect Dis. 2013 Mar 26;13:151. doi: 10.1186/1471-2334-13-151.
11. Vos MB, Kimmons JE, Gillespie C, Welsh J, Blanck HM. Dietary fructose consumption among US children and adults: the Third National Health and Nutrition Examination Survey. Medscape J Med.2008;10(7):160. [PMC free article].
12. Marriott BP, Cole N, Lee E. National estimates of dietary fructose intake increased from 1977 to 2004 in the United States. J Nutr. 2009;139(6):1228S–1235S.
13. Wiles NJ, Northstone K, Emmett P, Lewis G. ‘Junk food’ diet and childhood behavioural problems: results from the ALSPAC cohort. Eur J Clin Nutr. 2009;63(4):491–498.
14. Rogers EJ. Has enhanced folate status during pregnancy altered natural selection and possibly Autism prevalence? A closer look at a possible link. Med Hypotheses. 2008 Sep;71(3):406-10.
15. Surén P, et al. Association between maternal use of folic acid supplements and risk of autism spectrum disorders in children JAMA. 2013 Feb 13;309(6):570-7. doi: 10.1001/jama.2012.155925.
16. Piyathilake C, et al. Determinants of neural tube defect (NTD)-protective circulating concentrations of folate in women of child-bearing age in the US post-folic acid fortification era. Nutr Res Pract. 2013 Aug;7(4):315-25. doi: 10.4162/nrp.2013.7.4.315.
17. Kajta M, Wojtowitz AK. Impact of endocrine-disrupting chemical on neural development and the onset of neurological disorders. Pharmacological Reports, 2013, 65, 1632-1639.
18. Quaak I1, Brouns MR, Van de Bor M. The dynamics of autism spectrum disorders: how neurotoxic compounds and neurotransmitters interact. Int J Environ Res Public Health. 2013 Aug 6;10(8):3384-408. doi: 10.3390/ijerph10083384.
19. Meeker JD. Exposure to environmental endocrine disruptors and child development. Arch Pediatr Adolesc Med. 2012 Oct;166(10):952-8.
20. Nayar T, Zawia NH, Hood DB: Transplacental effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin on the temporal modulation of Sp1 DNA binding in the developing cerebral cortex and cerebellum. Exp Toxicol Pathol, 2002, 53, 461–468.
21. Kakeyama M, Sone H, Tohyama C: Changes in expression of NMDA receptor subunit mRNA by perinatal exposure to dioxin. Neuroreport, 2001, 12, 4009–4012.
22. Hatcher-Martin JM, Gearing M, Steenland K, Levey AI, Miller GW, Pennell KD: Association between polychlorinated biphenyls and Parkinson’s disease neuropathology. Neurotoxicology, 2012, 33, 1298–1304.
23. Parron T, Requena M, Hernández AF, Alarcón R: Association between environmental exposure to pesticides and neurodegenerative diseases. Toxicol Appl Pharmacol, 2011, 256, 379–385.
24. American Lung Association http://www.lung.org/…/…/sota-2013/state-of-the-air-2013.html.